Lymphocyte Subset Panel 7 - Congenital Immunodeficiencies

Casandra

Casandra Test Code AR17214Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0095899CPT Codes 86355, 86356, 86357, 86359, 86360

Lymphocyte Subset Panel 7 - Congenital Immunodeficiencies

Also known as: PIP

Clinical Use

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Use

The Lymphocyte Subset Panel 7 is a quantitative flow cytometry test used in the investigation of primary immunodeficiency disorders. This test evaluates and enumerates the percentages and absolute cell counts of lymphocyte subsets in lysed whole blood. It aids in identifying inherited immunodeficiencies, such as X-linked hypogammaglobulinemia, DiGeorge syndrome, bare lymphocyte syndrome, and severe combined immunodeficiency disease (SCID). The test helps in assessing defects in antibody formation, evaluating helper and cytotoxic T-cells, B-cells, and natural killer (NK) cells, and provides insight into the immune status of patients with suspected or known immunodeficiencies.

Special Instructions

Specimens must be analyzed within stability times provided. Some medications may affect immunophenotyping results and should be provided on the patient test request form. Hemogard tubes are preferred for laboratory automation and safety.

Limitations

This test does not detect all possible defects in immune function. Immunophenotyping is generally not useful in characterizing selective IgA deficiency, IgG subclass deficiencies, hyper IgM syndrome, or hyperimmunoglobulin E syndrome (Job syndrome). The test has not been cleared or approved by the US Food and Drug Administration but is performed in a CLIA certified laboratory and is intended for clinical purposes. Results must be interpreted within the context of the patient's clinical history and other laboratory findings. Delays in specimen processing and improper sample handling may affect test results.

Test Details

New York Approved