Measles (Rubeola) Antibodies, IgG and IgM
Also known as: MEASLE PAN
Use
The test aids in the diagnosis of measles infection. It is used to detect antibodies IgG and IgM which indicate whether there is a current or past exposure to measles or an immunization history. IgM presence suggests a recent primary infection, while IgG can indicate past exposure or immunization.
Special Instructions
The test may not be helpful in patients who have recently received an MMR vaccination. Parallel testing is preferred, and convalescent specimens must be received within 30 days from receipt of acute specimens. Clearly mark specimens as 'acute' or 'convalescent'.
Limitations
False-negative IgM results are possible if the specimen was collected too soon after exposure. Molecular testing may be helpful in such cases. False-positive IgM results are also possible. The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
New York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 5245-6
- 7962-4
Result Turnaround Time
1-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Serum separator tube
Collection Instructions
Separate serum from cells as soon as possible or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube.
Storage Instructions
Refrigerated.
Causes for Rejection
Unacceptable conditions are specified under individual components.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month (avoid repeated freeze/thaw cycles) |