Measles (Rubeola) Antibody, IgM by IFA
Also known as: MEASLES M
Use
This test aids in the diagnosis of acute measles infection by detecting IgM antibodies against the measles virus using a semi-quantitative indirect fluorescent antibody (IFA) method. The presence of IgM antibodies indicates a recent primary infection with measles virus. This test is particularly useful for clinicians when correlated with the patient's clinical presentation and history of exposure to the virus.
Special Instructions
It is recommended to collect serum samples and separate them as soon as possible. Parallel testing is preferred, and convalescent specimens must be received within 30 days of the acute specimens. Specimens should be marked as 'acute' or 'convalescent' for accurate processing.
Limitations
False-negative results may occur if the specimen is collected too early after exposure to the measles virus. False-positive results are also possible. It is advisable to conduct molecular testing if there is a need for more definitive conclusions about measles infection. Specimens that are bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid may be rejected.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IFA)
Biomarkers
LOINC Codes
- 5245-6
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum from cells as soon as possible or within 2 hours of collection.
Storage Instructions
Refrigerated. Stability after separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month (avoid repeated freeze/thaw cycles)
Causes for Rejection
Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |