MET Exon 14 Deletion Analysis by PCR

Casandra

Casandra Test Code AR18301Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 3003680CPT Code 81479

MET Exon 14 Deletion Analysis by PCR

Also known as: MET 14

Clinical Use

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Use

The MET Exon 14 Deletion Analysis by PCR test is designed to detect deletions in exon 14 of the MET gene, which are associated with cancer. Such genetic alterations can lead to constitutive activation of the MET receptor, contributing to tumor growth and progression. Identification of this mutation can help in tailoring personalized treatment strategies and determining eligibility for MET-targeted therapies.

Special Instructions

This test is not New York state approved. It is performed by a non-ARUP laboratory. A Non-Permitted Laboratory Request Form (NPL) must be submitted to the NYDOH prior to specimen collection. Ambient, tissue block or slides must be transported in a tissue transport kit provided by ARUP.

Limitations

The test is not performed at ARUP and involves separate submission when multiple tests are ordered. It only detects deletions within exon 14 of the MET gene and may not identify other alterations or mutations outside this region. The methodology may not be suitable for all specimen types or conditions of fixation.

Test Details