Methadone and Metabolite, Serum or Plasma, Quantitative

Also known as: METHADO SP

Clinical Use

Use

This test is used to monitor patient adherence to methadone therapy. It quantitatively measures methadone and its primary metabolite, EDDP, in serum or plasma. Monitoring methadone levels can help assess compliance, absorption, and appropriate timing of specimen collection relative to drug administration. It is intended for medical purposes only and not valid for forensic use.

Special Instructions

Not provided.

Limitations

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

Test Details

New York Approved

Methodology

Mass Spectrometry

Biomarkers

EDDP

Analyte

EDDP

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Methadone

Analyte

Methadone

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

3772-1 - Methadone SerPl-mCnc
60071-8 - EDDP SerPl-mCnc

Result Codes

3772-1 - Methadone SerPl-mCnc
60071-8 - EDDP SerPl-mCnc

Result Turnaround Time

1-7 days

Specimen

Serum

Volume

1 mL

Minimum Volume

0.5 mL

Container

ARUP standard transport tube

Collection Instructions

Separate serum or plasma from cells as soon as possible or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP standard transport tube.