Methadone and Metabolite, Urine, Quantitative
Also known as: CDCO METH
Use
The Methadone and Metabolite, Urine, Quantitative test is used to obtain quantitative results or to follow up a presumptive result for methadone. It is not intended for general screening; for such purposes, Methadone Urine Screen with Reflex to Quantitation is recommended. The test provides quantitative analysis of methadone and its primary metabolite, EDDP, to assess compliance with prescribed methadone therapy, evaluate potential drug misuse, and monitor therapeutic drug levels.
Special Instructions
Not provided.
Limitations
This test is for medical purposes only and is not valid for forensic use. The limitations include issues such as non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, and diluted or adulterated urine, which may result in the absence of expected drugs and metabolites. The concentration value must meet or exceed the cutoff of 100 ng/mL to be reported as positive. Testing limitations include inherent methodological and interpretative constraints; consult the laboratory for any specific interpretative questions.
Methodology
Mass Spectrometry
Biomarkers
EDDP
AnalyteMethadone
Analyte
LOINC Codes
- 3774-7 - Methadone Ur-mCnc
- 50542-0 - EDDP Ur-mCnc
Result Turnaround Time
1-7 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP standard transport tube
Storage Instructions
Room temperature.
Causes for Rejection
Specimens exposed to repeated freeze/thaw cycles.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 1 month |
| Frozen | 3 years |
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