Methanol
Also known as: METHANOL
Use
This test is used to monitor exposure to methanol, a toxic alcohol commonly found in antifreeze, solvents, and other industrial applications. Methanol exposure can occur through inhalation, ingestion, or dermal absorption. Measuring methanol levels is crucial for diagnosing methanol poisoning which can lead to severe metabolic acidosis, visual disturbances, and neurological impairments. Prompt identification and treatment are essential to prevent serious health consequences, including permanent vision loss and death.
Special Instructions
When drawing a blood specimen for alcohol testing, ensure a nonalcohol-based cleanser is used at the venipuncture site to avoid contamination. Timing of specimen collection should be dependent on the time of exposure, and specimens should be collected as soon as possible upon presentation to the hospital to ensure accurate results.
Limitations
The test has a limit of detection of 5 mg/dL, meaning concentrations below this level may not be accurately detected. While a toxic level is considered to be greater than 20 mg/dL, results must be interpreted in the context of the clinical picture as alcohol levels can vary with individual metabolism and exposure scenarios. It is also important to ensure proper specimen handling and transport to prevent alcohol loss or contamination, which could lead to erroneous results.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 5693-7
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate from cells ASAP or within 2 hours of collection. Cap tube tightly to minimize alcohol loss.
Patient Preparation
Use a nonalcohol-based cleanser at the venipuncture site.
Causes for Rejection
Whole blood. Plasma Separator Tubes (PST), Serum Separator Tubes (SST).
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 2 weeks |
| Frozen | 1 month |
