Methylphenidate and Metabolite Quantitative, Serum or Plasma
Also known as: METHYL SP
Use
The Methylphenidate and Metabolite Quantitative test, conducted on serum or plasma, is primarily used for monitoring patient adherence to medication regimes involving methylphenidate. Typical peak plasma concentrations are observed at 1 to 2 hours after administration of standard doses, making timely sample collection crucial to ensure accurate interpretation of adherence and therapeutic efficacy.
Special Instructions
Separate samples must be submitted when multiple tests are ordered as this test is not performed at ARUP. Samples should be collected 1-6 hours post-dose to attain optimal plasma concentrations for analysis.
Limitations
The test's performance characteristics have been assessed by NMS Labs and have not been cleared or approved by the FDA. Additionally, sample stability is crucial as ambient and refrigerated samples are unacceptable; only frozen samples up to 5 months are viable. Another limitation is the requirement of plasma concentrations being within a specific time post-dose for interpretation, mandating precise sample collection and handling.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 3807-5
- 32153-9
Result Turnaround Time
8-11 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.7 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate from cells ASAP or within 2 hours of collection.
Patient Preparation
Collect specimen 1-6 hours post dose.
Storage Instructions
CRITICAL FROZEN.
Causes for Rejection
Separator tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | Unacceptable |
| Frozen | 5 months |