Microsporidia by PCR
Also known as: MICROSPCR
Use
Microsporidia by PCR is preferred for diagnosing Microsporidia in immunocompromised patients experiencing persistent diarrhea when Encephalitozoon spp (E. intestinalis/E. hellem/E. cuniculi) or E. bieneusi is the suspected infectious agent. This qualitative test is crucial in detecting the presence of microsporidia DNA from stool samples, providing critical insights into managing infections in vulnerable populations.
Special Instructions
Not provided.
Limitations
A negative result from this polymerase chain reaction test does not discount the potential presence of polymerase chain reaction inhibitors in the patient specimen, nor does it indicate an absence of nucleic acids below the threshold level of detection. This limitation means that test outcomes could represent false negatives if inhibitors are present or nucleic acid levels are suboptimal for detection.
New York Approved
Methodology
PCR-based (PCR)
Biomarkers
Encephalitozoon spp. (E. intestinalis, E. hellem, E. cuniculi)
MicroorganismEnterocytozoon bieneusi
Microorganism
LOINC Codes
- 31208-2 - Specimen source
- 41443-3 - E bieneusi DNA Spec Ql NAA+probe
- 94333-2 - Encephalitozoon 18S rRNA Spec Ql NAA+prb
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Stool
Volume
1 mL
Minimum Volume
0.5 mL
Container
Unpreserved stool transport vial (ARUP supply #40910)
Storage Instructions
Frozen
Causes for Rejection
Specimens in Viral Transport Media. Stool in formalin.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 2 weeks |
| Frozen | 2 weeks |
Other tests from different labs that may be relevant