Myoglobin by Immunohistochemistry
Also known as: MYOGL IHC
Use
This test is designed primarily for the detection of the presence of myoglobin in tissues or cell preparations using immunohistochemical (IHC) staining technique. Myoglobin is a key biomarker often used in pathology to identify muscle tissue in samples, aiding in the diagnosis of muscle tumors, muscle diseases, and in forensic investigations. The IHC method provides a clear visualization of myoglobin presence, allowing pathologists to make informed decisions based on the staining patterns observed in tissue samples.
Special Instructions
Submit electronic request using ARUP Connect™ or by employing the ARUP Immunohistochemistry Stain Form (#32978) for those lacking electronic ordering capabilities. Typical shipping involves cooled containers during summer months to ensure specimen integrity. Additional information and technical assistance can be acquired through ARUP Client Services at (800) 522-2787.
Limitations
The test is limited to the qualitative detection of myoglobin using immunohistochemistry, which means it indicates presence but not concentration levels. It is a stain and return (technical) service, meaning that only the staining is performed and the interpretative analysis is left to the submitting pathologist. This test has not been cleared or approved by the FDA, and results should be integrated with other clinical findings and diagnostics. Specimens that do not contain representative tissue types or are depleted are considered unacceptable. This assay is stable indefinitely at room or refrigerated temperatures, but it cannot be frozen.
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue transport kit
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Prepare cells into a cellblock. Transport in a tissue kit.
Storage Instructions
Room temperature or refrigerated. Use a cooled container for shipping during summer months.
Causes for Rejection
Specimens submitted with non-representative tissue type or depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
