Myoglobin, Urine
Use
The Myoglobin, Urine test is used to measure the amount of myoglobin in urine. High levels of myoglobin in urine may indicate acute renal failure and other conditions involving muscle injury or damage, such as myocardial infarction or strenuous exercise. Usual results are less than 1 mg/L, and values between 1 and 15 mg/L are associated with vigorous exercise, myocardial infarction, or mild muscle injury. Levels above 15 mg/L increase the risk of acute renal failure.
Special Instructions
It is important to properly adjust the pH of the urine sample to 8-9 using Na2CO3 to ensure stability. The test is conducted on a random or 24-hour urine sample that should be collected and refrigerated. Following collection, the sample needs to be mixed thoroughly and treated or stored as specified.
Limitations
This test was developed and its performance characteristics determined by ARUP Laboratories, but it has not been cleared or approved by the US Food and Drug Administration. The test is performed in a CLIA certified lab for clinical purposes. Myoglobin is unstable in urine if the pH is not adjusted to the recommended range, which may affect the accuracy of the results.
New York Approved
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 2641-9
Result Turnaround Time
0-1 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Random or 24-hour urine. Refrigerate during collection. Thoroughly mix entire collection, then adjust pH to 8-9 using 10% Na2CO3 or use ARUP Standard Transport Tube prefilled with Sodium Carbonate.
Storage Instructions
Refrigerated
Causes for Rejection
Unstable pH not adjusted to 8-9
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 hours |
| Refrigerated | 72 hours |
| Frozen | 1 month |