Neisseria meningitidis Tetravalent Antibodies (Serogroups A, C, W-135 and Y), IgG
Also known as: NMENING
Use
This test is used to assess immunocompetence following Neisseria meningitidis vaccination. It evaluates the levels of IgG antibodies against four serogroups (A, C, W-135, and Y) to determine the protective response after vaccination. A low concentration suggests a lack of protection, while higher levels indicate a protective antibody response.
Special Instructions
For accurate results, it is important to clearly mark specimens as pre- or post-vaccine so they can be saved and tested simultaneously. Pre- and post-vaccination samples can be sent separately, but they must meet specific timing and storage requirements.
Limitations
This test should not be used for diagnosing an active infection or for serotyping Neisseria meningitidis. It is specifically designed for assessing antibody response post-vaccination and may not reflect the immune status related to ongoing or past infections. The test is developed by ARUP Laboratories and not FDA-approved.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 28546-0
- 28547-8
- 60465-2
- 60466-0
- 28546-0
- 28547-8
- 60466-0
- 60465-2
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1.5 mL
Minimum Volume
0.25 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Patient Preparation
Postimmunization specimen should be drawn 30 days after immunization.
Storage Instructions
Refrigerated. Stability: Ambient 48 hours, Refrigerated 2 weeks, Frozen 1 year (avoid repeated freeze/thaw cycles).
Causes for Rejection
Plasma or other body fluids. Contaminated, hemolyzed or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |