Non-Criteria Antiphospholipid Syndrome (APS) (aPs, aPt, aPs/aPt) Antibodies Panel
Also known as: NCAPS PAN
Use
This test is used for risk estimation of antiphospholipid syndrome (APS) when criteria antiphospholipid tests return negative or equivocal results. APS is an autoimmune disorder associated with recurrent thrombosis and pregnancy complications. The presence of antibodies against phosphatidylserine and prothrombin is evaluated to provide information on the risk of developing venous or arterial thrombosis.
Special Instructions
The test is approved for use in New York state. It serves as a second-line testing option for patients with APS when standard criteria tests do not provide conclusive information.
Limitations
Results from this test should not be used as a standalone diagnostic tool. They must be interpreted in conjunction with clinical findings and other criteria phospholipid antibody tests, as the isolated presence of antibodies may have questionable clinical significance. Positive results should be further confirmed with repeated testing using specimens collected at least 12 weeks apart to establish antibody persistence.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 32032-5
- 32033-3
- 40595-1
- 85359-8
- 85358-0
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1.5 mL
Minimum Volume
0.9 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Causes for Rejection
Heat-inactivated, grossly hemolyzed, icteric, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |