Octamer Transcription Factor-2 (Oct 2) by Immunohistochemistry
Also known as: OCT2 IHC
Use
Immunohistochemical detection of Octamer Transcription Factor‑2 (Oct‑2) is used as a technical stain to aid in diagnostic evaluation, particularly in distinguishing types of lymphoma such as classical Hodgkin lymphoma versus nodular lymphocyte‑predominant Hodgkin lymphoma. This test is performed as a stain‑and‑return (technical) service only and requires subsequent pathology consultation for full diagnostic interpretation.
Special Instructions
Submit electronic request or use ARUP Immunohistochemistry Stain Form (#32978) if electronic ordering is unavailable. Refer to ARUP Immunohistochemistry Stain Offerings brochure. Technical service only (stain and return).
Limitations
Interpretation by a pathologist is not included. Specimen quality is critical: non‑representative or depleted tissue is unacceptable. Paraffin sections should not be oven baked. Controls must show appropriate immunoreactivity. Technical performance only; requires appropriate clinical context and other diagnostic data for interpretation.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
5 unstained (3‑ to 5‑micron thick sections) (Min: 2 slides)
Container
tissue block or positively charged slides; deliver in ARUP tissue transport kit (#47808)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen; cells must be prepared into a cellblock; if sending precut slides, do not oven bake.
Storage Instructions
Protect paraffin block and/or slides from excessive heat; ship in cooled container during summer months.
Causes for Rejection
Non‑representative tissue type; depleted specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |