Octamer Transcription Factor-3 and -4 (Oct 3/4) by Immunohistochemistry
Also known as: OCT3/4 IHC
Use
This test is used for the detection and evaluation of Octamer Transcription Factor-3 and -4 (Oct 3/4), a crucial marker in identifying and studying pluripotent stem cells and germ cell tumors. The immunohistochemical staining technique allows for the visualization of the distribution and localization of Oct 3/4 within tissue samples, providing essential diagnostic and research information.
Special Instructions
This test is performed as a stain and return (technical) service only. It requires electronic ordering through ARUP’s system, or using an ARUP Immunohistochemistry Stain Form if electronic ordering is not available. Ensure proper use of ARUP client number for all submissions.
Limitations
The test has not been cleared or approved by the US Food and Drug Administration. Since it is a laboratory developed test conducted in a CLIA-certified laboratory, it is intended primarily for clinical purposes. The results are dependent on the quality and type of sample submitted.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue transport kit
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Transport tissue block or 5 unstained, positively charged slides (3- to 5-micron sections).
Storage Instructions
Protect paraffin block and/or slides from excessive heat. Ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with non-representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |