Osteocalcin by Electrochemiluminescent Immunoassay
Also known as: OSTEO NMID
Use
The Osteocalcin by Electrochemiluminescent Immunoassay is primarily used to assess bone metabolism and turnover, which is critical in the diagnosis and management of osteoporosis and metabolic bone diseases. It measures the osteocalcin levels in the blood, which can provide insight into bone formation rates. This test is valuable for monitoring treatment efficacy in patients receiving therapy for osteoporosis. Abnormal levels may indicate metabolic bone disorders or problems with bone turnover.
Special Instructions
Not provided.
Limitations
The test may not accurately reflect osteocalcin levels in patients with impaired renal function, as the osteocalcin result could be elevated due to impaired clearance or renal osteodystrophy. Pre-analytical variables such as sample handling and storage conditions can significantly affect test results, necessitating strict adherence to collection and processing instructions.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ECLIA)
Biomarkers
Osteocalcin
Protein
LOINC Codes
- 2697-1 - Osteocalcin SerPl-mCnc
Result Turnaround Time
0-1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
ARUP standard transport tube
Collection Instructions
Allow serum tube to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate serum or plasma from cells ASAP or within 2 hours of collection.
Storage Instructions
Frozen storage for specimen transport
Causes for Rejection
Hemolyzed specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 72 hours |
| Frozen | 3 months |
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