Use

This test is preferred for the initial diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) and for quantifying PNH clones. It is developed according to published guidelines and includes high-sensitivity testing for WBC and RBC with specific markers like FLAER and CD157. The test measures the most accurate size of the PNH clone using WBC analysis and provides quantification of Type II and Type III RBC clones. It helps in the management of PNH by identifying subclinical PNH populations in myelodysplastic bone marrow disorders, which may correlate with immunotherapeutic response.