Use

IgG and/or IgM antibodies to phosphatidylserine (aPS) may be associated with a positive test for anti-cardiolipin autoantibodies (aCL) and an increased risk for obstetric antiphospholipid syndrome (APS). In some cases, the presence of these antibodies may indicate possible APS or systemic lupus erythematosus (SLE). Clinical correlation is recommended, especially in the absence of lupus anticoagulant, IgG and/or IgM cardiolipin, and/or beta2 glycoprotein antibodies. It is necessary to interpret the results in conjunction with APS-specific clinical manifestations and other phospholipid antibody tests.