Plasminogen Activity
Also known as: PLG
Use
Plasminogen Activity testing is used to screen for plasminogen deficiency, a potential cause of thrombosis. It is not a primary diagnostic tool for inherited thrombotic or bleeding disorders. The test measures the functional activity of plasminogen, an important protein in the fibrinolytic system responsible for breaking down fibrin clots.
Special Instructions
Ensure separate specimens are submitted if multiple tests are ordered. Use a light blue (sodium citrate) tube for collection. Follow ARUP specimen handling guidelines for hemostasis/thrombosis to ensure sample integrity.
Limitations
This assay is not suitable for diagnosing hereditary thrombotic or bleeding disorders. Results can be affected by improper specimen handling, including hemolysis or clotting. Samples collected under suboptimal conditions may yield inaccurate results. The reference interval provided (71-144%) applies to individuals without known fibrinolytic function abnormalities.
New York Approved
Methodology
Chromogenic Assay
Biomarkers
LOINC Codes
- 28660-9
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP standard transport tube
Collection Instructions
Collect in a light blue (sodium citrate) tube. Transfer 1 mL of platelet-poor plasma to an ARUP standard transport tube.
Storage Instructions
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Causes for Rejection
Serum, EDTA plasma, clotted or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 hours |
| Refrigerated | Unacceptable |
| Frozen | 3 months |