Platelet Antibody (Glycoprotein) Plasma/Eluate
Use
This test is used for detecting platelet antibodies in plasma and eluate samples, which are associated with autoimmune thrombocytopenia (ITP). It involves a qualitative assay to identify autoreactive antibodies targeting platelet glycoproteins such as GP IIb/IIIa, GP Ib/IX, and GP Ia/IIa. The presence of such antibodies may support a diagnosis of ITP, although results must be interpreted cautiously as they cannot completely rule out the condition.
Special Instructions
Not provided.
Limitations
This test is not performed at ARUP, requiring separate specimens for multiple test orders. The test, developed by Versiti Wisconsin, Inc., is not FDA cleared or approved but is conducted for clinical purposes under CLIA certification. Test results should be interpreted carefully as antibodies detected may not always correlate with disease presence.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
Glycoprotein Ia/IIa
ProteinGlycoprotein Ib/IX
ProteinGlycoprotein IIb/IIIa
Protein
LOINC Codes
- 48594-6 - Plat Gp IIb/IIIa Ab Bld Ql IA
- 63478-2 - Plat Gp Ib/Ix Ab Bld Ql IA
- 63479-0 - Plat Gp Ia/IIa Ab Bld Ql IA
- 93479-4 - Observation Imp
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
40 mL
Minimum Volume
Not provided
Container
Yellow (ACD solution A or B)
Patient Preparation
Platelet transfusion given within 4 days of specimen collection may affect results.
Storage Instructions
CRITICAL REFRIGERATED.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 4 days |
| Frozen | Unacceptable |
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