Protriptyline, SP
Also known as: PROTRIP
Use
The Protriptyline, SP test is used to optimize dosing, monitor patient adherence, and ensure therapeutic levels of the drug protriptyline in patients undergoing treatment. It provides critical information to adjust dosages for maintaining therapeutic drug concentration, thereby minimizing the risk of adverse effects commonly associated with improper dosing.
Special Instructions
Specimen collection should be done as a predose (trough) draw at steady-state concentration for accurate assessment of drug levels.
Limitations
This test is developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. Interpretation of results should consider possible cross-reactivities with other substances and patient-specific factors that may affect drug levels. Therapeutic and toxic ranges are general guidelines, and medical discretion is advised in result interpretation.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 3999-0
Result Turnaround Time
2-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plain red, or lavender (K2 or K3EDTA) or pink (K2EDTA)
Collection Instructions
Separate serum or plasma from cells within 2 hours of collection. Transfer to an ARUP standard transport tube.
Patient Preparation
Timing of specimen collection: Predose (trough) draw at steady-state concentration.
Storage Instructions
Refrigerated.
Causes for Rejection
Whole blood, gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 5 days |
| Refrigerated | 2 weeks |
| Frozen | 6 months |
