Rubella Antibody, IgM
Also known as: RUBEIGM
Use
The Rubella Antibody, IgM test is used to detect the presence of IgM antibodies to rubella, which can indicate a current or recent rubella infection or immunization. This is critical for diagnosing ongoing infections particularly in pregnant women, as rubella infection during pregnancy can lead to serious birth defects.
Special Instructions
It is recommended not to use this test as a stand-alone diagnostic tool. Instead, the Rubella Antibodies, IgG and IgM panel (0050552) is preferred. Label specimens as 'acute' or 'convalescent' for identification. Proper handling and prompt processing of specimens are essential.
Limitations
Testing immediately post-exposure is of limited value without a later convalescent specimen. While the presence of IgM antibodies suggests a current or recent infection, low levels of IgM antibodies can persist for more than 12 months post-infection or immunization. The magnitude of the measured IgM result does not reflect the amount of antibody present.
New York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 5335-5
Result Turnaround Time
0-1 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Serum separator tube (SST), ARUP standard transport tube
Collection Instructions
Allow specimen to clot completely at room temperature then separate from cells as soon as possible or within 2 hours of collection.
Storage Instructions
Refrigerated
Causes for Rejection
Contaminated, heat-inactivated, icteric, or grossly hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year (avoid repeated freeze/thaw cycles) |