Serotonin, Whole Blood
Also known as: SEROT-WB
Use
Use to diagnose and monitor carcinoid tumors. Preferred serotonin test since most of the blood serotonin resides in the platelets. Metastasizing abdominal carcinoid tumors often show serotonin concentrations greater than 400 ng/mL. It may also show slight increases in conditions such as acute intestinal obstruction, acute MI, cystic fibrosis, dumping syndromes, and nontropical sprue.
Special Instructions
Medications such as lithium, MAO inhibitors, methyldopa, morphine, and reserpine may affect serotonin concentrations. Foods containing serotonin generally do not interfere significantly with the test.
Limitations
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. The test is performed in a CLIA certified laboratory and is intended for clinical purposes.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 2939-7
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
3 mL
Minimum Volume
1 mL
Container
ARUP Serotonin Transport Tube containing ascorbic acid
Collection Instructions
Collect in Lavender (EDTA) or pink (K2EDTA). Place on ice. Transfer to an ARUP Serotonin Transport Tube containing ascorbic acid. Mix well and freeze specimen within 2 hours of collection.
Patient Preparation
Abstain from medications for 72 hours prior to collection.
Storage Instructions
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Causes for Rejection
Non-frozen specimens. Specimens other than whole blood.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | Unacceptable |
| Frozen | 1 month |