Sotalol Quantitation, Serum/Plasma
Also known as: SOTA SP
Use
This test measures the concentration of sotalol in serum or plasma. Sotalol is a non-selective beta-blocker used to treat ventricular arrhythmias and atrial fibrillation. Accurate quantification is essential for therapeutic drug monitoring, ensuring efficacious drug levels while minimizing the risk of adverse effects, such as arrhythmias or hypotension due to toxicity. This test helps clinicians adjust medication dosages appropriately based on the patient's response and drug concentration.
Special Instructions
The test should be ordered alongside other tests separately as it is not performed at ARUP Laboratories. Collection requires either plain red, lavender, or pink (K2EDTA) tubes, and specimens should be separated from cells as soon as possible or within two hours of collection.
Limitations
The test is not approved by the FDA, and therefore, its performance characteristics are not endorsed by the agency. The test's effectiveness for diagnosing health conditions outside the stated objective is not established. Furthermore, it requires specific handling and processing to maintain the stability of the sample, as incorrect sample handling could lead to inaccurate results. The variability in processing could also affect the quantification of sotalol levels, impacting clinical decisions.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 12416-4
- 12416-4
Result Turnaround Time
8-11 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.2 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect in Plain Red, Lavender (EDTA), or Pink (K2EDTA). Separate from cells ASAP or within 2 hours.
Storage Instructions
Refrigerated; also acceptable: Room temperature or frozen.
Causes for Rejection
Separator tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 2 weeks |
| Refrigerated | 1 month |
| Frozen | 1 month |