STAT6 by Immunohistochemistry
Also known as: STAT6 IHC
Use
This immunohistochemical stain is a laboratory-developed test (LDT) performed by ARUP Laboratories, intended for clinical purposes to assess STAT6 protein expression in tissue specimens. The test assists in detecting nuclear STAT6 presence, which is diagnostically significant for entities such as solitary fibrous tumors / hemangiopericytomas, functioning as a diagnostic marker via staining of formalin-fixed paraffin‑embedded or cellblock tissue.
Special Instructions
This test is performed as a stain‑and‑return (technical) service only. It operates Monday through Friday and is New York state approved.
Limitations
This test has not been cleared or approved by the U.S. Food and Drug Administration, though it was developed and its performance characteristics were determined by ARUP Laboratories in a CLIA‑certified laboratory. Interpretation must be contextualized clinically. Specimens that are non‑representative tissue type or depleted are unacceptable. Frozen specimens are unacceptable. Slides must not be oven baked if precut, and need to be protected from excessive heat.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Transport tissue block or 5 unstained (3‑ to 5‑micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808 recommended but not required). (Min: 2 slides). If sending precut slides, do not oven bake.
Storage Instructions
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with non‑representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient: Indefinitely |
| Refrigerated | Refrigerated: Indefinitely |
| Frozen | Unacceptable |