Testosterone, Bioavailable and Total, Includes Sex Hormone-Binding Globulin (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy)
Also known as: BIO T MASS
Use
Provides a calculated value for bioavailable testosterone concentration using total testosterone measured by mass spectrometry. It may be used to evaluate hyperandrogenism in children and cisgender females, monitor testosterone-suppressing hormone therapies (such as antiandrogens or estrogens), evaluate testosterone status in individuals with protein-binding abnormalities, or assess hypogonadism in cisgender males.
Special Instructions
For individuals on testosterone-suppressing hormone therapies, refer to cisgender female reference intervals. Refer to the ARUP Testosterone Tests Comparison table for comparison with other testosterone tests.
Limitations
The test is developed and performed in a CLIA-certified laboratory and has not been cleared or approved by the FDA. Concentrations of free and bioavailable testosterone are derived from mathematical expressions based on constants for the binding of testosterone to albumin and/or sex hormone binding globulin.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 2986-8
- 49042-5
- 2990-0
- 13967-5
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.8 mL
Container
Serum separator tube or green (sodium or lithium heparin) tube
Collection Instructions
Separate serum or plasma from cells ASAP or within 2 hours of collection.
Patient Preparation
Collect between 6-10 a.m.
Storage Instructions
Refrigerated.
Causes for Rejection
EDTA plasma
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 6 months |