Testosterone, Free (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy)
Also known as: TESTOS FR
Use
The test provides a calculated value for free testosterone concentration using total testosterone measured by mass spectrometry. It is used to evaluate hyperandrogenism in children and cisgender females, monitor testosterone-suppressing hormone therapies (such as antiandrogens or estrogens), assess testosterone status in individuals with protein-binding abnormalities, and evaluate hypogonadism in cisgender males.
Special Instructions
To compare this test to other testosterone tests, refer to the ARUP Testosterone Tests Comparison table. Collect specimen between 6-10 a.m.
Limitations
The free testosterone concentration is estimated based on total testosterone measured by mass spectrometry and the binding constant of testosterone and sex hormone-binding globulin (SHBG). The test's performance characteristics were determined by ARUP Laboratories and it was performed in a CLIA certified laboratory but it has not been cleared or approved by the US FDA. Not applicable for individuals whose conditions do not match the established reference intervals.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 49042-5
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.8 mL
Container
Serum separator tube or green (sodium or lithium heparin).
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP standard transport tube.
Patient Preparation
Collect between 6-10 a.m.
Storage Instructions
Refrigerated.
Causes for Rejection
EDTA plasma.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 6 months |