Thyroglobulin Antibody
Also known as: ATHYG
Use
The Thyroglobulin Antibody test is primarily used to evaluate potentially unreliable thyroglobulin measurements, especially in cases of thyroid carcinomas. It is not recommended for the initial evaluation of autoimmune thyroid disease. Measuring thyroglobulin antibodies is crucial for patients with differentiated thyroid cancer to distinguish between antibody interference and genuine elevation of thyroglobulin levels.
Special Instructions
It is crucial to collect the specimen using a serum separator tube and transfer the serum appropriately to ensure accuracy. Heparinized plasma is also acceptable. Ensure that the specimen is not grossly hemolyzed or lipemic as these conditions are unacceptable.
Limitations
EDTA plasma specimens are not acceptable for this test. Additionally, the test may not accurately reflect disease state in patients with ongoing antibody interference. This test cannot be used as a standalone diagnostic tool for autoimmune thyroid diseases and should be used in conjunction with clinical evaluation and other diagnostic tests.
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 8098-6
Result Turnaround Time
0-1 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
ARUP standard transport tube
Collection Instructions
Collect using serum separator tube.
Causes for Rejection
Grossly hemolyzed or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 1 week |
| Frozen | 6 months |
