Thyroglobulin, Fine Needle Aspiration (FNA)
Also known as: THYROG FNA
Use
The Thyroglobulin, Fine Needle Aspiration (FNA) test is used in conjunction with fine needle aspiration biopsy of thyroid nodules to differentiate between benign and malignant nonmedullary thyroid nodules. As thyroglobulin is a protein produced by the thyroid gland, its presence in thyroid nodule aspirations can assist in diagnosing and managing thyroid cancer, particularly in cases where papillary or follicular thyroid cancer is suspected.
Special Instructions
It is important to note that the thyroglobulin result, regardless of concentration, should not be interpreted as absolute evidence for the presence or absence of papillary or follicular thyroid cancer. This test was developed by ARUP Laboratories and not cleared or approved by the FDA for use with FNA fluid. The test is performed in a CLIA certified laboratory for clinical purposes.
Limitations
Results obtained with different assay methods or kits cannot be used interchangeably, and the test should not be used as the sole diagnostic indicator of thyroid cancer. As specified, the assay used and reported values are not intended to be definitive evidence for the presence or absence of papillary or follicular thyroid cancer. Potential sample inadequacies such as the presence of cellular material or viscous specimens may lead to invalid results.
New York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 53922-1
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
0.5 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Centrifuge to remove cellular material. Specimen must be non-viscous and free of particulate matter. Indicate source on test request form.
Patient Preparation
Fine needle aspiration in saline.
Storage Instructions
Store and transport frozen.
Causes for Rejection
Specimen types other than those listed. Specimens containing EDTA. Viscous specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 1 week |
| Frozen | 6 months |