Transforming Growth Factor beta1, Plasma

Casandra

Casandra Test Code AR78412Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 3005863CPT Code 83520

Transforming Growth Factor beta1, Plasma

Also known as: TGFB1 PLA

Clinical Use

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Use

The Transforming Growth Factor beta1, Plasma test measures levels of TGF-b1 in plasma. TGF-b1 is a cytokine involved in regulating immune and inflammatory responses, and its measurement is useful in research into the pathophysiology of immune or inflammatory disorders. Elevated levels of TGF-b1 may be associated with various medical conditions, including scarring, fibrosis, and certain autoimmune diseases.

Special Instructions

Not provided.

Limitations

Results from this test are intended for research purposes and to understand the pathophysiology of immune or inflammatory disorders. This test is labeled as a Laboratory Developed Test (LDT) performed in a CLIA-certified laboratory and has not been cleared or approved by the U.S. Food and Drug Administration. Conventional specimen preparation practices may lead to elevated TGF-b1 measurements due to incomplete removal of platelets.

Test Details

New York Approved

Methodology

Immunoassay (ELISA)

Biomarkers

Transforming Growth Factor beta1

Protein

Quantitative Measurement

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

49853-5 - TGF-beta-1 SerPl-mCnc

Result Codes

49853-5 - TGF-beta-1 SerPl-mCnc

Result Turnaround Time

1-8 days

Specimen

Plasma

Volume

1 mL

Minimum Volume

0.3 mL

Container

ARUP standard transport tube

Collection Instructions

Centrifuge anticoagulated whole blood within 2 hours of collection at 1500g for 10 minutes. Collect plasma and transfer to a fresh tube. Immediately centrifuge plasma at 3000g for 10 minutes. Collect plasma from upper 2/3 of tube without disturbing the lower 1/3 and transfer to a fresh tube.