Tumor Necrosis Factor - alpha, Serum
Also known as: TNFA DO
Use
The Tumor Necrosis Factor - alpha, Serum test is primarily used for research purposes and helps to understand the pathogenesis of immune, infectious, allergic, or inflammatory disorders. It is utilized to explore the pathophysiology of these disorders and may be employed in clinical research to determine cytokine levels and their correlation with various pathological conditions.
Special Instructions
Cytokine levels may demonstrate diurnal variation. For longitudinal comparison, it is recommended that cytokine levels be determined at the same time of day. The test is developed by ARUP Laboratories as a Laboratory Developed Test (LDT) and is performed in a CLIA certified laboratory.
Limitations
The performance characteristics of this test have not been established by the US Food and Drug Administration. It is meant for clinical purposes and is not FDA-cleared. Refrigerated specimens are unacceptable; specimens should be separated from cells within 2 hours of collection and transferred for analysis as quickly as possible to prevent degradation.
New York Approved
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
LOINC Codes
- 3074-2
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect serum in a serum separator tube, or plain red. Separate serum from cells ASAP or within 2 hours of collection.
Storage Instructions
CRITICAL FROZEN. Ship in an ARUP Standard Transport Tube. Additional specimens must be submitted when multiple tests are ordered.
Causes for Rejection
Refrigerated specimens, contaminated or heat-inactivated specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 30 minutes |
| Refrigerated | Unacceptable |
| Frozen | 1 year |