Urea Clearance
Also known as: UNCL
Use
The Urea Clearance test is used to evaluate renal function by measuring the clearance of urea, a waste product of protein metabolism, from the blood by the kidneys. It provides insight into the kidney's ability to filter and excrete urea, helping to assess renal health and diagnose potential kidney disorders. The test is particularly useful in diagnosing and monitoring conditions such as acute and chronic kidney diseases, as well as glomerulonephritis and other nephropathies.
Special Instructions
Patient should refrigerate the 24-hour urine collection during the process. Both blood and urine samples need to be collected within a specified timeline to ensure accurate results. It's important to record the total urine volume and the collection time interval on the transport tube and test request form for accurate processing.
Limitations
The test may not provide accurate results in cases of fluctuating kidney function or when the collections are not performed correctly, such as incomplete urine collection or failure to refrigerate the sample. Certain medications or dietary factors could potentially influence urea levels. Random urine collections are not acceptable due to potential variability in urea excretion rates.
New York Approved
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
LOINC Codes
- 51735-9
- 12967-6
- 19153-6
- 30211-7
- 3094-0
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
3 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect 24-hour urine and refrigerate during collection. Transfer one 3 mL aliquot from a well-mixed 24-hour collection to an ARUP Standard Transport Tube.
Storage Instructions
Refrigerated
Causes for Rejection
Random urine collections.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 7 days |
| Frozen | 1 month |