Valproic Acid (Change effective as of 10/21/24: Refer to 0099310 in the October Hotline)
Also known as: VPA
Use
This test refers users to a current ARUP test (0099310) effective October 21, 2024; original Valproic Acid testing (0090290) has been replaced. The updated test includes measurement of free and total valproic acid, aiding in therapeutic drug management, especially in conditions with altered protein binding and drug–drug interactions.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (EIA)
Biomarkers
LOINC Codes
- 32283-4 - Valproate Free MFr SerPl
- 4086-5 - Valproate SerPl-mCnc
- 4087-3 - Valproate Free SerPl-mCnc
- 4086-5 - Valproate SerPl-mCnc
- 32283-4 - Valproate Free MFr SerPl
- 4087-3 - Valproate Free SerPl-mCnc
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Plain red
Collection Instructions
Pre‑dose (trough) draw at steady state; separate serum from cells within 2 hours of collection, transfer to ARUP Standard Transport Tube.
Storage Instructions
Refrigerated
Causes for Rejection
Light blue (citrate), gray (oxalate), green (heparin), K2EDTA plasma, tubes with liquid anticoagulant, or gel separator tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours after separation |
| Refrigerated | 1 week |
| Frozen | 1 month |
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