Varicella-Zoster Virus Antibody, IgG, CSF
Also known as: VZECSF
Use
The Varicella-Zoster Virus Antibody, IgG, CSF test detects antibodies to varicella-zoster virus in the cerebrospinal fluid (CSF). The presence of IgG antibodies may indicate a central nervous system infection or previous exposure to the virus. This test assists in diagnosing conditions such as varicella-zoster virus vasculopathy but is generally not recommended for the diagnosis of acute infections or encephalitis. It is important to consider possible contamination by blood or transfer of serum antibodies across the blood-brain barrier when interpreting results.
Special Instructions
This test is not New York state approved. Submit a Non-Permitted Laboratory Request Form to NYDOH prior to collection of the specimen. If approved and sample is received at ARUP, testing will proceed.
Limitations
The test cannot distinguish between a current or past varicella-zoster infection. Results may be affected by contamination from blood or if serum antibodies have crossed the blood-brain barrier. It is not suitable for diagnosing acute disease or encephalitis.
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 58755-0
- 58755-0
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
ARUP standard transport tube
Causes for Rejection
Contaminated, heat-inactivated, hemolyzed, or xanthochromic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |