von Willebrand Factor (VWF) Collagen III Binding
Also known as: VON WILLE
Use
The von Willebrand Factor (VWF) Collagen III Binding assay is used in the diagnosis and management of von Willebrand disease, a common hereditary bleeding disorder. The test measures the ability of the von Willebrand factor to bind to collagen, which is critical in the clotting process. This assessment helps in distinguishing between different types of von Willebrand disease and aids in determining the appropriate treatment plan.
Special Instructions
This test is not performed at ARUP Laboratories directly; therefore, separate specimens must be submitted if multiple tests are ordered. The test is performed by a non-ARUP laboratory, Versiti Wisconsin, Inc. All specimens must be transported frozen to maintain integrity.
Limitations
The test's performance characteristics are determined by Versiti Wisconsin, Inc, and it has not been cleared or approved by the FDA. The test should be used as a clinical aid, not as a sole diagnostic tool. Analytical performance may vary between batches and laboratories due to the nature of enzyme-linked immunosorbent assays.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 89366-9
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
0.5 mL
Minimum Volume
0.5 mL
Container
ARUP standard transport tube
Collection Instructions
Collect using a light blue (sodium citrate) tube.
Storage Instructions
CRITICAL FROZEN.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | Unacceptable |
| Frozen | 2 weeks |
