von Willebrand Panel (Change effective as of 01/20/26: Refer to 3020169 in the January Hotline)
Also known as: VW PANEL
Use
This panel is the recommended initial workup for suspected von Willebrand disease (VWD), providing quantitative and functional assessment of von Willebrand factor along with Factor VIII activity to distinguish between quantitative and qualitative deficiencies.
Special Instructions
Not provided.
Limitations
Specimens must be platelet‑poor plasma collected in sodium citrate, frozen and submitted separately when multiple tests are ordered; unsuitable specimens (e.g., serum, EDTA plasma, clotted or hemolyzed samples) are unacceptable. VWF levels may be affected by acute phase reactions, stress, blood type, and pre-analytic variables.
New York Approved
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
Factor VIII, Activity
Analytevon Willebrand Factor, Activity (GPIbM)
Analytevon Willebrand Factor, Antigen
Analyte
LOINC Codes
- 3209-4 - Fact VIII Act/Nor PPP
- 107372-5 - GPIbM Act/Nor PPP
- 27816-8 - vWF Ag Act/Nor PPP IA
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
3 mL platelet‑poor plasma
Minimum Volume
1 mL
Container
Lt. blue (sodium citrate) tube
Collection Instructions
Collect sodium citrate plasma; separate specimens must be submitted when multiple tests are ordered.
Storage Instructions
CRITICAL FROZEN
Causes for Rejection
Serum, EDTA plasma, clotted or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 hours |
| Refrigerated | Unacceptable |
| Frozen | 3 months |
Other tests from different labs that may be relevant