Chromosome Analysis - Prenatal - Amniotic Fluid
Use
Chromosome Analysis - Prenatal - Amniotic Fluid is crucial in examining chromosomal abnormalities that could affect fetal development. It is performed on amniocytes for prenatal diagnosis, employing G-banding techniques to visualize chromosomes. The analysis can detect various anomalies like aneuploidy and structural rearrangements, informing patients of potential risks associated with genetic conditions. Diagnostic clarity regarding chromosomal integrity enables healthcare providers to guide expectant parents in making informed decisions about their pregnancy management.
Special Instructions
Fetal cell cultures will be held for seven days post-report issuance. If no further testing is initiated within this window, cultures will be discarded.
Limitations
The standard methodology may miss subtle rearrangements or low-level mosaicism, as well as microdeletions or microduplications needing more sensitive tools like Chromosomal Microarray Analysis. Results should not rule out undetected birth defects or genetic conditions, potentially requiring further testing based on clinical indications.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
14 days
Related Documents
For more information, please review the documents below
Specimen
Amniotic Fluid (Unknown)
Volume
20-30 cc
Minimum Volume
15 mg
Container
two sterile 15 ml conical centrifuge tubes
Collection Instructions
Collect 20-30 cc of fluid in two sterile 15 ml conical centrifuge tubes. Discard the first 2 cc of fluid collected.
Storage Instructions
Ship the sample at room temperature to the laboratory by overnight express.
Causes for Rejection
Specimen cannot be frozen.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hrs |