Casandra

Casandra Test Code BA81788Version 1 (DRAFT)

Performing Lab

Lab Baylor GeneticsLab Test ID 4900CPT Codes 82540, 82542, 83789, 83919, 84510, 82379, 84260, 84377, 84425, 84446, 84525, 84550, 84590, 82016, 84252, 84210, 84035, 82128, 82180, 82239, 82247, 82383, 84207, 82465, 82528, 82533, 82565, 82725, 82726, 82746, 82760, 82947, 82978, 83150, 83605, 83945, 82507

Global Metabolomic Assisted Pathway Screen (Global MAPS)®-Plasma

Clinical Use

Order Test

Use

Metabolomic profiling is a large-scale, semi-quantitative screening test that assesses perturbations in various biochemical pathways, including those related to amino acids, organic acids, lipids, and nucleotides. This screening tool is particularly useful for individuals displaying an undifferentiated phenotype or equivocal mutations in metabolic process-related genes. However, it should not replace existing diagnostic tests or be used for therapy monitoring. It's crucial to confirm any abnormalities highlighted by this profile through diagnostic biochemical or molecular methods. This test requires a physician's order and should include comprehensive clinical information for optimal interpretation.

Special Instructions

For accurate results, conditions affecting metabolic processes such as liver or kidney failure, chemotherapy, or specialized diets may hinder test interpretation. Consultation with a laboratory director is recommended under these circumstances. The test is ineffective for screening lysosomal storage disorders or related large molecule disorders. Detailed clinical context is mandatory for insightful analysis. Results are for screening purposes and require further confirmation through definitive tests.

Limitations

Interpretations of the Global MAPS results could be complicated under certain conditions including liver failure, kidney failure, and various health treatments or dietary practices. These conditions may yield uninterpretable findings or obscure the results. It is critical to perform follow-up testing for confirmation of any detected anomalies and to approach the results as supplementary information rather than conclusive evidence on their own. The test will identify known metabolites but should not be utilized as a definitive diagnostic tool for conditions where specific small molecule metabolite testing is not available.

Test Details