Hematology Profile Plus Panel
Use
The Hematology Profile Plus Panel is designed to assess 302 DNA genes and over 1600 RNA genes associated with hematologic neoplasms. It specifically helps in the evaluation of conditions such as myelodysplastic syndrome, acute myeloid leukemia, and VEXAS syndrome. This test is particularly beneficial for oncology patients presenting with hematologic malignancies, facilitating early diagnosis and potentially guiding treatment decisions based on molecular abnormalities. It leverages advanced genomic techniques to provide a comprehensive profile, aiding clinicians in understanding disease mechanisms and tailoring patient management strategies accordingly.
Special Instructions
It is advised that samples are received by the laboratory within 72 hours for accurate results. After this timeframe, only DNA results may be included, possibly affecting the completeness of the test outcomes. Proper handling and timely shipping of the specimens are vital to ensure the integrity of the sample and the reliability of the test results. Users should adhere to the shipping guidelines to mitigate any risk of sample degradation.
Limitations
The test results may be influenced by various factors, including sample quality, timing, and the presence of interfering substances. Results should be interpreted within the context of the patient's clinical history and other diagnostic findings. The detection limits and potential for false negatives or positives due to technical limitations are acknowledged in the interpretation of results. Care should be taken with variant analysis, as not all detected variants will have established clinical significance. This test is designed primarily for use in patients with a clinical suspicion of hematologic neoplasms, and inappropriate application may lead to misinterpretation.
New York Approved
Methodology
NGS (Targeted)
Biomarkers
Result Turnaround Time
14 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood (Fresh)
Volume
5-10 mL
Minimum Volume
5 mL
Container
EDTA (purple-top) tube
Collection Instructions
Draw blood in EDTA (purple-top) tube(s) and send 5-10 mL.
Storage Instructions
Ship at ambient temperature (18-25°C/64-77°F) in an insulated container by overnight courier. Specimen should arrive in the laboratory within 48 hrs of collection. Do not heat or freeze.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |