Special Instructions

For patients with a history of allogeneic bone marrow or stem cell transplant, or those with hematological conditions with circulating tumor cells, using a non-blood derived sample, such as cultured fibroblasts, is recommended. For detailed specimen requirements, refer to the Specimen Requirements page or contact the Clinical team at (800) 436-3037.

Limitations

The assay achieves >99% analytical sensitivity and specificity for single nucleotide variants, insertions and deletions <15bp, and exon-level deletions/duplications. Larger insertions/deletions may have reduced sensitivity. Single-exon copy number events may not be detected due to sequence properties or data quality. Structural rearrangements, complex sequences, some non-coding regions, and details like mosaicism may not be detectable. The test analyzes extracted genomic DNA, which may not represent the constitutional genome in rare cases (e.g., hematolymphoid neoplasm, bone marrow transplant).

Biomarkers

Result Turnaround Time

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