17-OH Progesterone, LC/MS, Six Specimens
Use
The 17-OH Progesterone test, utilizing Liquid Chromatography-Mass Spectrometry (LC/MS), measures the level of 17-OH Progesterone in blood. This test is typically used for assessing adrenal function and aiding in the diagnosis of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency, the most common form of CAH. The test series involves collecting multiple specimens to monitor how 17-OH Progesterone levels change over time, especially after the administration of medication or other stimuli to understand adrenal response.
Special Instructions
This test is a series panel that requires multiple blood samples to be collected at different times. It begins with a baseline sample, followed by administration of a drug or treatment, and subsequent sample collections. Ensure coordination with the clinician ordering the test to determine the necessity for the series and the specific protocol to follow.
Limitations
The test should not be conducted unless coordinated with the clinician to ascertain the purpose of the series order. The results can be affected by time of collection, patient preparation, and adherence to the timing protocol. False elevations or reductions may occur if the samples are not timed appropriately relative to administration of the treatment.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 27996-8
- 51680-7
- 12716-7
- 12717-5
- 12718-3
- 12719-1
- 46963-5
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Collect an initial tube as a baseline. Administer the drug or other treatment, then collect additional tubes at specified intervals.
Causes for Rejection
Improper timing of sample collection, hemolysis, inadequate labeling of specimens.