17-OH Progesterone, LC/MS, Three Specimens
Use
The 17-OH Progesterone, LC/MS, Three Specimens test is utilized to assess the levels of 17-hydroxyprogesterone in the blood. This hormone, produced in the adrenal gland and gonads, is an intermediate product in the biosynthesis of glucocorticoids and androgens. The test is typically used in the assessment of congenital adrenal hyperplasia (CAH), a group of genetic conditions limiting hormone production in the adrenal glands. Diagnosing CAH can assist in the management and understanding of conditions influenced by adrenal androgens, including early puberty and adrenal tumors.
Special Instructions
This test requires multiple blood samples collected at different time intervals after the administration of a treatment or drug. It is crucial to follow the specific instructions from the Endocrine Appendix of the LabCorp Directory of Services for multiple specimen testing. This series should not be initiated without understanding the clinical rationale and ensuring treatment administration following the initial sample draw.
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration. This assay may not detect other circulating steroids that could cross-react with the 17-OH Progesterone, potentially leading to inaccurate results in certain contexts.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 27996-8
- 51680-7
- 12716-7
- 46963-5
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
Not provided
Minimum Volume
Not provided
Container
Multiple tubes
Collection Instructions
Collect an initial baseline blood sample, administer the treatment or drug as instructed, and then collect additional samples at designated time intervals.
Causes for Rejection
Inadequate volume, improper labeling, or incorrect collection timing.