Adrenocorticotropic Hormone (ACTH), Plasma, Three Specimens
Use
The Adrenocorticotropic Hormone (ACTH), Plasma, Three Specimens test is used in the diagnostic assessment of adrenal gland disorders such as Cushing's disease and Addison's disease. ACTH is a hormone produced by the pituitary gland that regulates cortisol production by the adrenal glands. Measuring ACTH levels at multiple time points can help evaluate adrenal function and diagnose disorders related to cortisol imbalance.
Special Instructions
This panel requires multiple tubes to be collected at different time points: an initial baseline, followed by additional specimens collected after pharmacological or medical intervention. Ensure the clinician is contacted prior to collection to confirm series ordering. Patients should refrain from biotin supplementation for at least 72 hours prior to specimen collection to avoid assay interference.
Limitations
This test may exhibit interference from high doses of biotin supplements. Result interpretation requires careful timing and coordination with medical treatment to ensure accurate assessment of adrenal function. Reference ranges may vary depending on the time of day the samples are collected, with specific intervals established for morning collections.
Methodology
Other
Biomarkers
LOINC Codes
- 12458-6
- 39564-0
- 42598-3
- 46963-5
- 42598-3
- 46963-5
- 39564-0
- 12458-6
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
Patient Preparation
Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.