ALK Gene Rearrangements
Also known as: Vysis ALK Break Apart FISH Probe Kit
Use
Confirmation/identification of non−small-cell lung cancer (NSCLC) patients who may be eligible for targeted therapy, as this is an FDA‑approved test for identification of ALK rearrangements in NSCLC tumor specimens.
Special Instructions
Pertinent clinical diagnosis, including the pathology report documenting pulmonary origin, should be included with the specimen. Additional charges will be applied for the embedding process if formalin‑fixed tissue is submitted.
Limitations
Not provided.
FDA Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
4-6 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Five slides (4‑ to 5‑micron thick sections)
Minimum Volume
Two slides (4‑ to 5‑micron thick sections)
Container
Paraffin block
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Improper embedded prep; poor fixation 72 hours; decalcified bones or bone core; broken or dirty slides; absence of tumor or quantity not sufficient for analysis