Allergen Profile With Component Reflexes, Respiratory–Area 16

Casandra

Casandra Test Code LC07526Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 607005CPT Codes 82785, 86003

Allergen Profile With Component Reflexes, Respiratory–Area 16

Clinical Use

Use

Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.

Special Instructions

Specimens should be collected in a red-top or gel-barrier tube and stored at room temperature. Turnaround time is typically 3–5 days, but additional time may be needed for confirmatory or reflex tests. Testing schedules may vary.

Limitations

The results should be interpreted in the context of a patient's clinical history. Although component IgE testing can enhance evaluation over whole extracts alone, levels of specific IgE to components such as Fel d 1 or Can f 1 should be seen as potentially indicative of cross-reactivity, and not solely as an allergy to the specific animal. The interpretation should consider the possibility of molecular cross-reactivity and the context of symptoms.

Test Details