Allergen Profile With Component Reflexes, Respiratory–Area 17
Use
Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.
Special Instructions
If Dog IgE levels are ≥0.35 kU/L, additional IgE testing for Can f 1, Can f 2, Can f 3, Can f 4, Can f 5, and Can f 6 will be conducted. If Cat IgE levels are ≥0.35 kU/L, further IgE testing will be performed for Fel d 1, Fel d 2, Fel d 4, and Fel d 7.
Limitations
The test relies on specific IgE measurements, which may not be elevated in all individuals with allergies. Medications or conditions affecting the immune response could influence results. Accurate interpretation requires clinical correlation, as IgE levels alone do not confirm a clinical allergy. Test results should be considered alongside patient history and other diagnostic tests.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 8251-1
- 19113-0
- 6096-2
- 6095-4
- 6833-8
- 6098-8
- 6265-3
- 6078-0
- 6212-5
- 6075-6
- 6025-1
- 6020-2
- 7155-5
- 15284-3
- 15283-5
- 6178-8
- 6189-5
- 6109-3
- 33982-0
- 6090-5
- 6278-6
- 6085-5
- 7604-2
- 6244-8
- 6186-1
- 6181-2
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.5 mL
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Inadequate labeling; gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 18 months |
