Allergen Profile With Component Reflexes, Respiratory–Area 18

Casandra

Casandra Test Code LC88633Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 606980CPT Codes 82785, 86003

Allergen Profile With Component Reflexes, Respiratory–Area 18

Clinical Use

Use

Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.

Special Instructions

If Dog IgE is ≥0.35 kU/L, additional IgE testing for specific Canine allergens such as Can f 1 through Can f 6 will be conducted. Similarly, if Cat IgE is ≥0.35 kU/L, further testing for specific Feline allergens Fel d 1, Fel d 2, Fel d 4, and Fel d 7 will be performed.

Limitations

Results should be interpreted in context with patient's clinical history. Use of component IgE testing may provide a more detailed evaluation over the use of whole extracts alone, but it requires careful correlation with clinical findings to determine the extent and relevance of sensitization.

Test Details