Allergen Profile With Component Reflexes, Respiratory–Area 3
Use
Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.
Special Instructions
Testing involves component IgE analysis to enhance the evaluation of allergic individuals over whole extracts alone. These results should be interpreted within the context of the patient's clinical history. Reflex testing is automatically performed if certain thresholds are met for dog or cat IgE.
Limitations
The test results should be considered alongside the patient's clinical history for accurate diagnosis and management. While component testing offers more detailed allergenic profiles, cross-reactivity with other mammalian proteins could lead to broader sensitization assessments. Moreover, for accurate IgE quantifications related to specific allergens in canines and felines, results should be compared at the molecular component level rather than the whole extract.
Methodology
Immunoassay (Proteomic Panel)
Biomarkers
LOINC Codes
- 8251-1
- 19113-0
- 6096-2
- 6095-4
- 6833-8
- 6098-8
- 6041-8
- 6034-3
- 6265-3
- 6078-0
- 6212-5
- 6075-6
- 6025-1
- 6020-2
- 7155-5
- 15283-5
- 6178-8
- 6189-5
- 6109-3
- 6209-1
- 6085-5
- 7604-2
- 6244-8
- 6186-1
- 6181-2
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.5 mL
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Inadequate labeling; gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 18 months |
