Allergen Profile With Component Reflexes, Respiratory–Area 4
Use
Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.
Special Instructions
If Dog IgE ≥0.35 kU/L, IgE for Can f 1, Can f 2, Can f 3, Can f 4, Can f 5 and Can f 6 will be performed. If Cat IgE ≥0.35 kU/L, IgE for Fel d 1, Fel d 2, Fel d 4 and Fel d 7 will be performed.
Limitations
The results from component IgE testing should be interpreted considering the patient's clinical history due to potential cross-reactivity between different allergens. While component testing can provide detailed insights into specific allergen sensitizations, its results are influenced by various factors such as the individual's clinical condition and potential cross-reactivity among similar proteins from different sources.
Methodology
Immunoassay (Thermo Fisher ImmunoCAP®)
Biomarkers
LOINC Codes
- 8251-1
- 19113-0
- 6096-2
- 6095-4
- 10921-5
- 6833-8
- 6098-8
- 6041-8
- 6034-3
- 6265-3
- 6078-0
- 6212-5
- 6075-6
- 6025-1
- 6020-2
- 7155-5
- 6178-8
- 6189-5
- 6109-3
- 6282-8
- 6085-5
- 7604-2
- 6244-8
- 6186-1
- 6181-2
- 78384-5
- 19732-7
- 64976-4
- 94278-9
- 58773-3
- 58772-5
- 19738-4
- 82543-0
- 64973-1
- 94277-1
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.5 mL
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Inadequate labeling; gross hemolysis
