Allergen Profile With Component Reflexes, Respiratory–Area 7
Use
Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.
Special Instructions
ImmunoCAP testing is performed especially when there is concern about potential anaphylaxis, and in cases where immunotherapy or other therapeutic measures based on skin testing results have not led to satisfactory symptom remission.
Limitations
Results should be interpreted in the context of clinical history as component IgE testing may offer enhanced evaluation over whole extracts alone, though cross-reactivity between allergens might complicate interpretation. Proper allergy sensitization testing can provide future prognostic indicators and inform treatment plans, but multiple sensitizations, particularly to lipocalins from furry animals, are associated with respiratory allergic diseases.
Methodology
Immunoassay (Thermo Fisher ImmunoCAP®)
Biomarkers
LOINC Codes
- 8251-1
- 19113-0
- 6096-2
- 6095-4
- 6833-8
- 6098-8
- 6041-8
- 6265-3
- 6078-0
- 6212-5
- 6075-6
- 6025-1
- 6020-2
- 7155-5
- 6178-8
- 15283-5
- 6189-5
- 6109-3
- 6090-5
- 6278-6
- 6281-0
- 6085-5
- 6234-9
- 6232-3
- 6186-1
- 6181-2
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.5 mL
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Inadequate labeling; gross hemolysis
